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Sodium Stearyl Fumarate CAS 4070-80-8

CAS No.:

4070-80-8

Formula:

C22H39NaO4

EINECS:

223-781-1

Packing:

25KG/DRUM

Trademark:

samreal

Place of Origin:

China

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Sodium Stearyl Fumarate CAS 4070-80-8

This product is an off-white crystalline powder, slightly soluble in methanol and soluble in hot water. It is typically prepared by the reaction of stearyl alcohol with maleic anhydride, followed by isomerization and salt formation to obtain sodium stearyl fumarate.

Product Details

ITEM	SPECIFICATION
Description	White or almost white, fine powder with agglomerates of flat, circular particles.
Solubility	Practically insoluble in water, slightly soluble in methanol, practically insoluble in acetone and in anhydrous ethanol.
Identification	IR
Water	≤5.0%
Lead	≤ 10ppm
Saponification value (anhydrous basis)	142.2-146.0
Limit of sodium stearyl maleate and stearyl alcohol
--sodium stearyl maleate	≤0.25%
--stearyl alcohol	≤0.5%
Related substances
--sodium stearyl maleate	≤0.25%
--stearyl alcohol	≤0.5%
--Max single impurity	≤0.5%
--Total impurities	≤5.0%
Residual solvents
--Ethanol --Ethyl acetate --Toluene	NMT 5000ppm NMT 5000ppm NMT 890ppm
Assay	99.0%-101.5%
Storage	Room temperature, shade, Airtightness

Product Advantages

It is compatible with the vast majority of APIs and serves as an excellent alternative to magnesium stearate.

It is insensitive to mixing time; prolonged mixing time has minimal impact on the disintegration, hardness and dissolution of tablets.

As a hydrophilic lubricant, it is significantly superior to magnesium stearate in terms of tablet disintegration, hardness and dissolution, making it the first choice for poorly soluble drugs.

Product Applications

Sodium stearyl fumarate is a widely used pharmaceutical excipient and the preferred choice of hydrophilic lubricants.

As a lubricant for tablets and capsules, sodium stearyl fumarate is typically used at a dosage of 0.5%~2.0%. It can address many problems associated with stearate-based lubricants and improve drug disintegration. Thanks to its good hydrophilicity, it has little impact on the dissolution of drugs in tablets.

In effervescent tablets, sodium stearyl fumarate can form a protective film, which improves disintegration and promotes dissolution, thereby enhancing bioavailability.

Sodium stearyl fumarate can also be used as a dough quality improver at a dosage of 0.5%. Adding it to pasta products can improve the toughness and enhance the taste of flour-based foods.

Sodium stearyl fumarate is non-toxic and non-irritating. It is absorbable by the human body and converted into stearyl alcohol and fumaric acid. The former is further oxidized to stearic acid—both stearyl alcohol and stearic acid are major components of natural foods. The latter is a normal component of human tissues. Therefore, sodium stearyl fumarate can be used as a fumaric acid supplement and serve as a source of fumaric acid.

FAQ

The target market of our brand has been continuously developed over the years. For more information, please reach our team, we are more than happy to help.

Can I get samples?

Yes, some samples are available for free, while the courier cost is afforded by thebuyers.

When Can l Get The Quotation?

Our sales team will reply within 24 hours on working days.

What's Your M0Q?

For a courier delivery orderthe MOQ is normally 100 g~1 kg; For an air transportorder or sea delivery order ,the MOQ is usually 25 kgs.

What's Your Delivery Time?

For a courier delivery order, delivery time is usually 5~7 working days. For an airtransport order,usually around 7~10 working days. For an sea delivery order ,usually around 10~20 working days.

How Do You Treat Quality Complaint?

First of all, our quality control will reduce the quality problem to near zero. lf thereis a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

How To Contact Us?

You can send Mail:biz.chem@samreal.com; Or you can call us directly.

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