What is the drug niclosamide?
Niclosamide is a pesticide designed for controlling oncomelania and molluscs. It is effective in killing Oncomelania hupensis in fresh water, with efficacy against both snail bodies and snail eggs. Additionally, it can be used as an anthelmintic for eliminating Taenia saginata and Taenia solium.
1. Basic Product Information
English Name: Niclosamide
Molecular Formula: C₁₃H₈Cl₂N₂O₄
CAS Number: 50-65-7
2. Physicochemical Properties: The product is slightly soluble in ethanol, chloroform or ether, but almost insoluble in water. Its melting point ranges from 228 to 232℃.
3. Quality Test Results
Appearance: White fine powder (Complies with standard)
Identity: Positive (Complies with standard)
Chlorides: ≤500 ppm (Complies with standard)
5-chlorosalicylic acid: ≤60 ppm (Complies with standard)
2-chloro-4-nitroaniline: ≤100 ppm (Complies with standard)
Related substances: ≤0.2% (Test result: 0.16%)
Loss on drying: ≤0.5% (Test result: 0.36%)
Sulphated ash: ≤0.1% (Test result: 0.05%)
Melting point: 227.0~232.0℃ (Test result: 229.0~229.7℃)
Assay: 98.0%~101% (Test result: 98.16%)
Conclusion: Complies with BP2019 standard.
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